NetScaler appliance can now be used to run XenApp Web Interface. In the past it could only be run on Windows based servers. Some of the benefits are 1. Web Interface deployments are mainly HTTPS based, high-end Netscaler boxes can offload SSL processing on hardware, lot more CPU cycles will be available for WI related processing on Netscaler boxes compared to normal windows servers and hence WI running on high end Netscaler boxes can definitely give better Web Interface performance when https protocol is used for connection. 2. Web Interface sites can be managed via NetScaler’s Admin UI